Toxicology and Clinical Pharmacology Service
RESEARCH GROUP MEMBERS
1 Afio Bertolini
2 Carla Bazzani
3 Maria M. Cainazzo
4 Anna Ferrari
5 Daniela Giuliani
6 Salvatore Guarini
7 Sheila Leone
8 Chiara Mioni
9 Alessandra Ottani
10 Luigi A. Pini
AFFILIATION
1 University of Modena and Reggio Emilia, Italy
GROUP DATA
Address Largo del Pozzo, 71 - 41100 Modena, Italy.
Phone +39-0594224699
Fax +39-0594224069
E-mail bertolini.alfio@unimore.it
Web Site 
RESEARCH TOPICS
1 Pathophysiology of ischemia and ischemia-reperfusion
2 Pathophysiology of headache
3 Drug abuse and underlying mechanisms
4 Pharmacology of behavior disturbances (feeding behavior, sexual behavior, depression)
ASSISTANCE ACTIVITIES
1 Treatment of Drug Abuse
2 Laboratory of Toxicology and Clinical Pharmacology
3 Diagnosis and treatment of headache
EDUCATION IN TOXICOLOGY
1 Post-graduate School in "Clinical Pharmacology"
2 Post-graduate School in “Medical Toxicology”
3 Master in “Treatment of pain, and palliative therapies”
SERVICES
1 Laboratory of Toxicology and Clinical Pharmacology
2 Center of Excellence for the Study and Treatment of Headache
3 Information on Doping Substances
COLLABORATIONS
1 Sezione di Pavia del Centro Interuniversitario di Ricerca su “CEFALEE E DISORDINI ADATTATIVI (UCADH)”
2 Dipartimento di Neuroscienze“B. B. Brodie” Università di Cagliari
3 Dipartimento di Neurologia, Sezione di Farmacologia, Università di Siena
4 Dipartimento di Patologia Umana, Dipartimento di Medicina Sperimentale, Università di Pavia
5 Dipartimento Clinico-Sperimentale di Medicina e di Farmacologia, Facoltà di Medicina, Università di Messina
6 Department of Neuroscience, University of Uppsala
7 Dipartimento di Anatomia Patologica, Università di Milano - Bicocca
8 Ospedale Maggiore di Milano
9 Dipartimento di Farmacologia, Chemioterapia e Tossicologia “E. Trabucchi”, Università Statale di Milano
10 Dipartimento di Farmacologia, Facoltà di Medicina, Università di Catania
11 Istituto di Farmacologia, Università di Brescia
12 Dipartimento di Medicina Interna, Università di Milano
13 Ospedale Niguarda - Ca' Granda, Milano
PUBLICATIONS
1 Bertolini A, Ottani A, Sandrini M (2002). Selective COX-2 inhibitors and dual acting anti-inflammatory drugs: critical remarks. Curr Med Chem 9:1033-1043.
2 Ottani A, Saltini S, Bartiromo M, Zaffe D, Botticelli AR, Ferrari A, Bertolini A, Genedani S (2003). Effect of g-hydroxybutyrate in two rats models of focal cerebral damage. Brain Res 986:181-190.
3 Ferrari A, Sternieri E, Ferraris F, Bertolini A (2003). Emerging problems in the pharmacology of migraine: interactions between triptans and drugs for prophylaxis. Pharmacol Res 48:1-9.
4 Guarini S, Altavilla D, Cainazzo MM, Giuliani D, Marini H, Squadrito G, Minutoli L, Bertolini A, Marini R, Adamo EB, Venuti FS and Squadrito F (2003). Efferent vagal fibre stimulation blunts NF-kaB activation and protects against hypovolemic hemorrhagic shock. Circulation 107:1189-1194.
5 Mioni C, Giuliani D, Cainazzo MM, Leone S, Iannone C, Bazzani C, Grieco P, Novellino E, Tomasi A, Bertolini A, Guarini S (2003). Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors. Eur J Pharmacol 477: 227-234.
6 Guarini S, Cainazzo MM, Giuliani D, Mioni C, Altavilla D, Marini H, Bigiani A, Ghiaroni V, Passaniti M, Leone S, Bazzani C, Caputi AP, Squadrito F, Bertolini A (2004). Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal antinflammatory pathway. Cardiovascular Research 63:357-365.
7 Ferrari A, Ottani A, Bertolini A, Cicero AF, Coccia CP, Leone S, Sternieri E (2005). Adverse reactions related to drugs for headache treatment: clinical impact. Eur J Clin Pharmacol 60:893-900.
  Ultimo aggiornamento: Dicembre 2005