Department of Environmental Health Sciences
RESEARCH GROUP MEMBERS
1 Roberto Fanelli
2 Luisa Airoldi
3 Roberta Pastorelli
4 Emilio Benfenati
5 Chiara Chiabrando
6 Enrico Davoli
7 Ettore Zuccato
8 Elena Fattore
9 Renzo Bagnati
AFFILIATION
1 Mario Negri Institute for Pharmacological Research
GROUP DATA
Address Via Eritrea 62, 20157 Milano, Italy
Phone +39-0239014498
Fax +39-0239001916
E-mail fanelli@marionegri.it
Web Site www.marionegri.it
RESEARCH TOPICS
1 Study of pathogenic models and the mechanism of action of toxic compounds using proteomics tools
2 Assessment of human exposure to environmental toxic compounds by molecular epidemiology methods, including the identification characterization and measurement of new biomarkers
3

Evaluation of the environmental and health risks associated with environmental factors by applying existing procedures and by developing new predictive models; Characterization/measurement of toxic compounds in environmental samples through the development and use of innovative analytical methods, instrumentation, software for data acquisition /management, and modeling
4 Safety assessment of contaminants in food through exposure evaluation of human populations
SERVICES
1 Analytical services for the measurements of environmental toxic compounds
EDUCATION IN TOXICOLOGY
1 The Department is tutoring PhD students in collaboration with the Open University (London, UK)
COLLABORATIONS
1 National Collaborations with the principal Institutions and Universities in Italy.
2 International Collaborations with Institutions and Universities in Europe, USA
PUBLICATIONS
1 Magagnotti C, Pastorelli R, Pozzi S, Andreoni B, Fanelli R, Airoldi L (2003). Genetic polymorphisms and modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in human lymphocytes. Int J Cancer 107:878-884.
2 Vineis P, Veglia F, Benhamou S, Butkiewicz D, Cascorbi I, Clapper M L, Dolzan V, Haugen A, Hirvonen A, Ingelman-Sundberg M, Kihara M, Kiyohara C, Kremers P, Le Marchand L, Ohshima S, Pastorelli R, Rannug A, Romkes M, Schoket B, Shields P, Strange R C, Stucker I, Sugimura H, Garte S, Gaspari L (2003). CYP1A1 T3801 C polymorphism and lung cancer: A pooled analysis of 2,451 cases and 3,358 controls. Int J Cancer 104:650-657.
3 Citerio G, Nobili A, Airoldi L, Pastorelli R, Patrono A (2003). Severe intoxication after phenytoin infusion: a pharmacogenetic preventable adverse reaction. Neurology 60:1395-96.
4 Chiabrando C, Fanelli R, Lucca U (2003). Peripheral biomarkers of oxidative damage in Alzheimer's disease. Ann Neurol 53:419-420.
5 Pastorelli R,Carpi D,Airoldi L,Chiabrando C,Bagnati R,Fanelli R,Moverare S,Ohlsson C Proteome analysis for the identification of in vivo estrogen-regulated proteins in bone Proteomics 2005;5:4936-4945.
6 Mazzatorta P,Smiesko M,Lo Piparo E,Benfenati E QSAR model for predicting pesticide aquatic toxicity J Chem Inf Model 2005;45:1767-1774.
7 Zuccato E, Chiabrando C, Castiglioni S, Calamari D, Bagnati R, Schiarea S, Fanelli R
Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse
http://www.ehjournal.net/content/4/1/14 2005.
  Ultimo aggiornamento: Dicembre 2005