Lab. of Toxicology
RESEARCH GROUP MEMBERS
1 Corrado Lodovico Galli
2 Marina Marinovich
3 Emanuela Corsini
4 Barbara Viviani
5 Laura Lucchi
6 Stefano Bartesaghi
AFFILIATION
1 Dipartimento Scienze Farmacologiche (http://users.unimi.it/~spharm/isf.html)
Facoltà di Farmacia.(http://www.unimi.it/ateneo/facol/farmacia.htm)
Università degli Studi di Milano (http://www.unimi.it/)
GROUP DATA
Address Via Balzaretti, 9, 20133 MILANO
Phone 02-50318-315 (Galli); -316 (Marinovich)
Fax 02-50318260
E-mail Corrado.Galli@unimi.it
Marina.Marinovich@unimi.it
Web Site  
RESEARCH TOPICS
1 Identification of the mechanism of action of toxic substances at molecular level and its relevance for human risk assessment
2 Neuron-glia interactions in neurodegeneration
3 Immunotoxicology: 1) development of in vitro tests for discrimination between allergens and iritants 2) immunosenescence (identification of molecular changes related to immunological function decline in the elderly)
4 Nanotoxicology
EDUCATION IN TOXICOLOGY
1 Toxicology for Degrees in Pharmacy, CTF and Environmental Toxicology
2 “European Master in Risk Assessment and Risk Analysis” - in co-operation with the Universities of Milan (Italy), Utrecht (NL), and Surrey (UK) (2002-2004)
SERVICES
1 Pesticide Registration (Directive 91/414/EEC)
Advice and technical support to the Italian Ministry of Health, as well as to the European Commission, for the peer-review process of active ingredients and plant protection products (PPPs), in the frame of Council Directive EEC/91/414 on the authorization of pesticides at Member State and European level
2 European Commission and EFSA (European Food Safety Authority)
Participation in EC scientific committees (as active members or invited experts), on matters concerning the safety of cosmetics for consumers
3 Italian Ministry of Health
Participation as members of the National Advisory Committee on Pesticide Products of the Italian Ministry of Health, on matters concerning evaluation and authorization of Plant Protection Products in Italy
COLLABORATIONS
1 Karolinska Institutet (Stockolm, Sweden) (Sten.Orrenius@imm.ki.se)
2 RITOX (University of Utrecht), The Netherlands, (R. Pieters@RITOX.vet.uu.nl)
3 MRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, P.O. Box 138, Leicester LE1 9HN U.K, Pierluigi Nicotera
PUBLICATIONS
1 Reactive oxygen species generated by glia are responsible for neuron death induced by human immunodeficiency virus-glycoprotein 120 in vitro. B. Viviani, E. Corsini, M. Binaglia, C.L. Galli, M. Marinovich. Neuroscience, 2001, 107, 51-58.
2 Facilitation of acetylcholine signaling by the dithiocarbamate fungicide propineb. M. Marinovich, B. Viviani, V. Capra, E. Corsini, L. Anselmi, G. 'Agostino, A. Di Nucci, M. Binaglia, M. Tonini, C.L. Galli. Chem. Res. Toxicol., 2002, 15, 26-32.
3 The anti-inflammatory activity of estrogen in glial cells is regulated by the PKC-anchoring protein RACK-1. B. Viviani, E. Corsini, M. Binaglia, L. Lucchi, C. L. Galli, M. Marinovich. J. of Neurochem. 2002, 83, 1180-1187.
4 Induction of Adipose Differentiation Related Protein and neutral lipid droplet accumulation in keratinocytes by skin irritants. E. Corsini, B. Viviani, O. Zancanella, L. Lucchi, F. Visioli, G. Serrero, S. Bartesaghi, C.L. Galli, M. Marinovich. J Invest. Dermatol. 2003, 121, 337-344.
5 Resistance to acute silicosis in senescent rats: role of alveolar macrophages. E. Corsini, A. Giani, L. Lucchi, S. Peano, B. Viviani, C. L. Galli, M Marinovich. Chem. Res. Toxicol., 2003, 16, 1520-1527.
6 Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor. B. Viviani, S. Bartesaghi, E. Corsini, P. Villa, P. Ghezzi, A. Garau, C. L. Galli, M. Marinovich J. Neurochem, 93(2):412-21, 2005.
7 Cytokines role in neurodegenerative events. B. Viviani, S. Bartesaghi, E. Corsini, C.L. Galli, M.Marinovich Toxicology Letters 2004, 149, 85-9.
  Ultimo aggiornamento: Dicembre 2005