| Laboratories of Cellular and Genetic Toxicology |
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| RESEARCH GROUP MEMBERS |
| 1 |
Patrizia Hrelia |
| 2 |
Giorgio Cantelli Forti |
| 3 |
Carmela Fimognari |
| 4 |
Francesca Maffei |
| 5 |
Andrea Tarozzi |
| 6 |
Sabrina Angelini |
| 7 |
Fabio Carbone |
| 8 |
Monia Lenzi |
| 9 |
Alessandra Marchesi |
| 10 |
Fabiana Morroni |
| 11 |
Davide Sciuscio |
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| AFFILIATION |
| 1 | Department of Pharmacology, University of Bologna |
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| RESEARCH TOPICS |
| 1 |
Toxic stress response in human cell lines |
| 2 |
Biomarkers and genetic/carcinogenic risk in
human populations |
| 3 |
Natural substances and chemoprevention of cancer |
| 4 |
Food toxicology |
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| EDUCATION IN TOXICOLOGY |
| 1 | Toxicology, Toxicology II, Environmental and occupational Toxicology, Food Toxicology, Applied Toxicology (Chemistry and Pharmaceutical Technologies degree) |
| 2 | Food and environmental Toxicology, Safety of cosmetic products (Pharmacy degree) |
| 3 | Molecular and Cellular Toxicology (Pharmaceutical Biotechnologies degree) |
| 4 | Toxicology, Food and environmental Toxicology, Applied Toxicology, Safety of cosmetic products (Quality Control of Health Products) |
| 5 | Toxicology (Scientific Information on Pharmaceutical Products) |
| 6 | Carcinogenesis, mutagenesis and teratogenesis I, Toxicology II, Nutrition Toxicology (Post graduated School in Toxicology) |
| 7 | Toxicology (Post graduated School in Hygiene and Preventive Medicine) |
| 8 | Toxicology (Post graduated School in Hospital Pharmacy) |
| 9 | Seminars in Toxicology (Ph.D. on Pharmacology and Toxicology) |
| 10 | Genotoxic risk assessment and EC white book on chemical substances (Master on Polymeric Materials and Environmental Chemistry, University of Ferrara), Safety and Innovation (Master on Pharmaceutical Management and Health Policy, University of Bologna). |
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| SERVICES |
| 1 |
Referee for Apoptosis, Cancer Research, Cellular
and Molecular Life Sciences, Chemico-Biological Interactions, Environmental
and Molecular Mutagenesis, Environmental Toxicology and Pharmacology,
Leukemia and Lymphoma, Oncogene, Mutation Research, Cancer Letters,
J. Nutrition, Science of the Total Environment, Environmental Research,
Pharmacological Research, Regulatory Toxicology and Pharmacology,
J. of Pharmacy and Pharmacology. |
| 2 |
Editor of the Italian Society of Toxicology
Newsletter (PH) |
| 3 |
Member of the Committee for Environmental Protection,
University of Bologna.(PH) |
| 4 |
Member of the PRIN Panel of referees |
| 5 |
President of the Italian Society of Toxicology
(GCF) |
| 6 |
Member of the Directorate-General Health and
Consumer Protection, Scientific Committee on the Toxicity, Ecotoxicity
and the Environment in EU (GCF). |
| 7 |
Member of the National Committee for the Basic
Sciences Research grants (FIRB projects) (GCF). |
| 8 |
Member of the scientific local 06 Committee
for the ex-60% grants (CF). |
| 9 |
Member of Medical Science Monitor International
Reviewers Panel (CF). |
| 10 |
Professional advice to state ministries, municipal
law courts, industries, national and international bodies, the media
on questions related to the health risk of chemicals. |
| 11 |
Establishment of the laboratories under GLP
guidelines in an academic setting (since 1989). |
| 12 |
Organization of courses for pharmacists, medical
doctors on Pharmacology and Toxicology |
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| COLLABORATIONS |
| 1 |
National Cancer Research Institute, Genoa,
Italy; |
| 2 |
Karolinska Institut, Department of Environmental
Medicine at Stockholm, Sweden; |
| 3 |
Flow Cytometry Laboratories at the GSF Center
in Munich, Germany; |
| 4 |
The University of Texas Medical Branch at Galveston,
TX, USA; |
| 5 |
CSIRO Health Sciences and Nutrition in Adelaide,
Australia. |
| 6 |
German Cancer Research Center. Heidelberg, Germany |
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| PUBLICATIONS |
| 1 |
Angelini S, Kumar R, Carbone F, Maffei F, Cantelli-Forti
G, Violante FS, Lodi V, Curti S, Hemminki K, Hrelia P (2005). Micronuclei
in humans induced by exposure to low level of ionizing radiation:
influence of polymorphisms in DNA repair genes. Mutat Res 570:105-117. |
| 2 |
Fimognari C, Sangiorgi L, Capponcelli S, Nüsse
M, Fontanesi S, Berti F, Soddu S, Cantelli-Forti G, Hrelia P (2005).
A mutated p53 status did not prevent the induction of apoptosis
by sulforaphane, a promising anti-cancer drug. Inv New Drugs 23:195-203. |
| 3 |
Fimognari C, Berti F, Nüsse M, Cantelli-Forti
G, Hrelia P (2004). Induction of apoptosis in two human leukemia
cell lines as well as differentiation in human promyelocytic cells
by cyanidin 3-O-beta glucopyranoside. Biochem Pharmacol 67:2047-2056. |
| 4 |
Tarozzi A, Marchesi A, Cantelli-Forti G, Hrelia
P (2004). Cold-storage affects antioxidant properties of apples
in Caco-2 cells. J Nutr 134:1105-1109. |
| 5 |
Hrelia P, Tarozzi A, Cantelli-Forti G (2003).
Diet and risk of cancer. Lancet 361:258. |
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