| Laboratory of Industrial Toxicology |
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| RESEARCH GROUP MEMBERS |
| 1 | Maurizio Manno |
| 2 | Carmine Sbordone |
| 3 | Pier Paolo Piccoli |
| 4 | Luisa Padovano |
| 5 | Monica De Mare |
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| AFFILIATION |
| 1 | University of Naples Federico II, Dept. of Preventive Medical Sciences, Section of Occupational Medicine |
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| RESEARCH TOPICS |
| 1 |
Occupational toxicology of industrial chemicals |
| 2 |
Mechanisms of cytochrome P450-dependent activation
and toxicity of chemicals |
| 3 |
Methods for human CYP phenotyping |
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| EDUCATION IN TOXICOLOGY |
| 1 | Postgraduate Degree in Occupational Medicine – Course of Occupational Toxicology, University of Naples Federico II |
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| SERVICES |
| 1 | Occupational Health Service and Laboratory of Industrial Toxicology of the University of Naples Federico II |
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| COLLABORATIONS |
| 1 | Prof. Giovanni Battista Bartolucci, Univ. of Padua |
| 2 | Prof. Massimo Valoti, Univ. of Siena |
| 3 | Prof. Mariaenrica Fracasso, Univ. of Verona |
| 4 | Prof. Nicola Sannolo, II Univ. of Naples |
| 5 | Prof. Arnulfo Albores, CINVESTAV (Mexico City) |
| 6 | Prof. Wolfgang Dekant, Univ. of Wuerzburg (Germany) |
| 7 | Prof. Francesco De Matteis, Univ. of London (U.K.) |
| 8 | Prof. Francois Berthou, Univ. of Brest (France) |
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| PUBLICATIONS |
| 1 |
A. Mendoza-Cantù, F. Castorena-Torres,
M. Bermúdez de León, B. Cisneros, L. López-Carrillo,
A.E. Rojas-García, A. Aguilar-Salinas, M. Manno & A.
Albores: Occupational toluene exposure induces Cytochrome P450 2E1
mRNA expression in peripheral lymphocytes. Environ Health Persp
2005 (in press). |
| 2 |
Fustinoni S, Perbellini L, Soleo L, Manno M,
Foà V. Biological monitorino in occupational exposure to
low levels of 1,3-butadiene. Toxicol Lett 149: 353-360 (2004). |
| 3 |
P. Apostoli, A. Mangili & M.Manno: Relationship
between PCBs in blood and D-glucaric acid in urine. Toxicol.
Lett. 144:17-26 (2003). |
| 4 |
A. Zanovello, R. Ferrara & M. Manno: Reductive
activation of HCFC123 by methaemalbumin. Toxicol. Lett. 144:127-136
(2003). |
| 5 |
S. Bortolato, A. Zanovello, M. Rugge, M. Brotto,
S. Marini, P.G. Gervasi & M. Manno: Trifluoroacethylated proteins
in liver and plasma of guinea pigs treated with HCFC-123 and halothane.
Toxicol. Lett. 144:35-47 (2003). |
| 6 |
L.F. Oropeza-Hernandez, B. Quintanilla-Vega,
R. A. Reyes-Mejia, C. J. Serrano, E.A. Garcia-Latorre, W. Dekant,
M. Manno & A. Albores: Trifluoroacethylated adducts in spermatozoa,
testes, liver and plasma and CYP2E1 induction in rats after subchronic
inhala-tory exposure to halothane. Toxicol. Lett. 144:105-116
(2003). |
| 7 |
Apostoli P, Neri G, Lucas D, Manno M. Berthou
F (2003). Influence of genetic polymorphism of CYP1A1 and
GSTM1 on urinary levels of 1-hydroxypyrene. Toxicol Lett
144:27-34. |
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